The Mayo Clinic says CJD, the disease caused by prions, is 100% fatal and has no treatment. Some of the symptoms of CJD (prion disease) described by the Mayo Clinic include:Stroke-like symptomsDifficulty speakingConfusionOdd movementsOther symptoms include emotional changes, a sharp loss of cognitive function and seeming personality changes. It all ends in death. Once the prion symptoms are evident, it’s already too late. There is no treatment and no reversal possible.